Atadja, P.: search on Z-Library

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1

Development of the pan-DAC inhibitor panobinostat (LBH589): Successes and challenges

Journal:

Year:

2009

Language:

english

File:

PDF, 287 KB

english, 2009

2

Epigenetic Silencing of the Tetraspanin CD9 during Disease Progression in Multiple Myeloma Cells and Correlation with Survival

De Bruyne, E., Bos, T. J., Asosingh, K., Vande Broek, I., Menu, E., Van Valckenborgh, E., Atadja, P., Coiteux, V., Leleu, X., Thielemans, K., Van Camp, B., Vanderkerken, K., Van Riet, I.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

3

The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity

Woods, David M., Woan, Karrune, Cheng, Fengdong, Wang, Hongwei, Perez-Villarroel, Patricio, Lee, Calvin, Lienlaf, Maritza, Atadja, Peter, Seto, Edward, Weber, Jeffrey, Sotomayor, Eduardo M., Villagra,

Journal:

Melanoma Research

Year:

2013

Language:

english

File:

PDF, 614 KB

english, 2013

4

Selective Growth Inhibition of Tumor Cells by a Novel Histone Deacetylase Inhibitor, NVP-LAQ824

Journal:

Cancer Research

Year:

2004

Language:

english

File:

PDF, 569 KB

english, 2004

5

584 POSTER Histone deacetylase inhibitors abrogate the levels and activity of estrogen receptor (ER) α and histone deacetylase (HDAC) 6 in human breast cancer cells (BCCs)

W. Fiskus, A. Mohapatra, P. Bali, M. Balasis, R. Rao, P. Atadja, J. Wu, K. Bhalla

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 60 KB

english, 2006

6

Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies

DeAngelo, D J, Spencer, A, Bhalla, K N, Prince, H M, Fischer, T, Kindler, T, Giles, F J, Scott, J W, Parker, K, Liu, A, Woo, M, Atadja, P, Mishra, K K, Ottmann, O G

Journal:

Year:

2013

Language:

english

File:

PDF, 593 KB

english, 2013

7

Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain

Senisterra, Guillermo, Zhu, Hugh Y., Luo, Xiao, Zhang, Hailong, Xun, Guoliang, Lu, Chunliang, Xiao, Wen, Hajian, Taraneh, Loppnau, Peter, Chau, Irene, Li, Fengling, Allali-Hassani, Abdellah, Atadja, P

Journal:

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

8

Polycomb Target Genes Are Silenced in Multiple Myeloma

Kalushkova, Antonia, Fryknäs, Mårten, Lemaire, Miguel, Fristedt, Charlotte, Agarwal, Prasoon, Eriksson, Maria, Deleu, Sarah, Atadja, Peter, Österborg, Anders, Nilsson, Kenneth, Vanderkerken, Karin, Öb

Journal:

Year:

2010

Language:

english

File:

PDF, 1.91 MB

english, 2010

9

Combination Strategy Targeting the Hypoxia Inducible Factor-1 with Mammalian Target of Rapamycin and Histone Deacetylase Inhibitors

Verheul, H. M.W., Salumbides, B., Van Erp, K., Hammers, H., Qian, D. Z., Sanni, T., Atadja, P., Pili, R.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 606 KB

english, 2008

10

Role of CAAT/Enhancer Binding Protein Homologous Protein in Panobinostat-Mediated Potentiation of Bortezomib-Induced Lethal Endoplasmic Reticulum Stress in Mantle Cell Lymphoma Cells

Rao, R., Nalluri, S., Fiskus, W., Savoie, A., Buckley, K. M., Ha, K., Balusu, R., Joshi, A., Coothankandaswamy, V., Tao, J., Sotomayor, E., Atadja, P., Bhalla, K. N.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 991 KB

english, 2010

11

Differential effects of transforming growth factor-β1 on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in young and old human fibroblasts

Dylan R. Edwards, Kevin J. Leco, Paul P. Beaudry, Peter W. Atadja, Claude Veillette, Karl T. Riabowol

Journal:

Experimental Gerontology

Year:

1996

Language:

english

File:

PDF, 1.35 MB

english, 1996

12

SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-κB/STAT3 complex to its promoter in malignant lymphoid cells

Scuto, A, Kirschbaum, M, Buettner, R, Kujawski, M, Cermak, J M, Atadja, P, Jove, R

Journal:

Cell Death and Disease

Year:

2013

Language:

english

File:

PDF, 1.79 MB

english, 2013

13

Inhibition of Histone Deacetylases Promotes Ubiquitin-Dependent Proteasomal Degradation of DNA Methyltransferase 1 in Human Breast Cancer Cells

Zhou, Q., Agoston, A. T., Atadja, P., Nelson, W. G., Davidson, N. E.

Journal:

Molecular Cancer Research

Year:

2008

Language:

english

File:

PDF, 539 KB

english, 2008

14

Abrogation of MAPK and Akt Signaling by AEE788 Synergistically Potentiates Histone Deacetylase Inhibitor-Induced Apoptosis through Reactive Oxygen Species Generation

Yu, C., Friday, B. B., Lai, J.-P., McCollum, A., Atadja, P., Roberts, L. R., Adjei, A. A.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 833 KB

english, 2007

15

Current trends in outwitting resistance development in Candida infections through photodynamic and short peptide therapies: a strategic-shift from conventional antifungal agents

Bengyella, louis, Waikhom, Sayanika Devi, Atadja, Peter W.

Journal:

Expert Review of Anti-infective Therapy

Year:

2016

Language:

english

File:

PDF, 991 KB

english, 2016

16

Induction of cell cycle arrest and DNA damage by the HDAC inhibitor panobinostat (LBH589) and the lipid peroxidation end product 4-hydroxynonenal in prostate cancer cells

Piergiorgio Pettazzoni, Stefania Pizzimenti, Cristina Toaldo, Paula Sotomayor, Luigina Tagliavacca, Song Liu, Dan Wang, Rosalba Minelli, Leigh Ellis, Peter Atadja, Eric Ciamporcero, Mario Umberto Dian

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 1.52 MB

english, 2011

17

251 Histone deacetylase inhibition — a promising anticancer therapeutic strategy

P. Atadja, M. Hsu, P. Kwon, R. Pili, K. Bhalla, A. Wood

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 141 KB

english, 2004

18

Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia

Salmon, Jessica M, Bots, Michael, Vidacs, Eva, Stanley, Kym L, Atadja, Peter, Zuber, Johannes, Johnstone, Ricky W

Journal:

Clinical Epigenetics

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

19

161 POSTER Potent anticancer activity of panobinostat (LBH589) in models of hormone-refractory prostate cancer (HRPC): targeting the androgen receptor

W. Shao, J. Growney, G. O'Connor, Y. Feng, H. Scher, Y.M. Yao, S. Fawell, P. Atadja

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

20

Histone deacetylase inhibitors activate NF-κB in human leukemia cells through an ATM/NEMO-related pathway.

Rosato, Roberto R., Kolla, Sarah S., Hock, Stefanie K., Almenara, Jorge A., Patel, Ankita, Amin, Sanjay, Atadja, Peter, Fisher, Paul B., Dent, Paul, Grant, Steven

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 49 KB

english, 2016

21

Regulation of Gene Expression and Transcription Factor Binding Activity during Cellular Aging

Meyyappan, Muthupalaniappan, Atadja, Peter W., Riabowol, Karl T.

Journal:

Year:

1996

Language:

english

File:

PDF, 1.44 MB

english, 1996

22

Epigenetic modulation of radiation response in human cancer cells with activated EGFR or HER-2 signaling: Potential role of histone deacetylase 6

In Ah Kim, Mina No, Jang Mi Lee, Jin Hee Shin, Jee Sun Oh, Eun Jung Choi, Il Han Kim, Peter Atadja, Eric J. Bernhard

Journal:

Radiotherapy and Oncology

Year:

2009

Language:

english

File:

PDF, 710 KB

english, 2009

23

Regulation of transcription factor activity during cellular aging

Wheaton, Keith, Atadja, Peter, Riabowol, Karl

Journal:

Biochemistry and Cell Biology

Year:

1996

Language:

english

File:

PDF, 1.71 MB

english, 1996

24

Increased Activity of p53 in Senescing Fibroblasts

Peter Atadja, Howard Wong, Igor Garkavtsev, Claude Veillette and Karl Riabowol

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.29 MB

english, 1995

25

Effect of the histone deacetylase inhibitor LBH589 against epidermal growth factor receptor dependent human lung cancer cells

Edwards, A., Li, J., Atadja, P., Bhalla, K., Haura, E. B.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 962 KB

english, 2007

26

Fibronectin induces the perivascular deposition of cerebrospinal fluid-derived amyloid-β in aging and after stroke

Howe, Matthew D., Atadja, Louise A., Furr, J. Weldon, Maniskas, Michael E., Zhu, Liang, McCullough, Louise D., Urayama, Akihiko

Journal:

Neurobiology of Aging

Year:

2018

Language:

english

File:

PDF, 5.06 MB

english, 2018

27

Overexpression of Cyclin D1 Blocks Proliferation of Normal Diploid Fibroblasts

Peter Atadja, Howard Wong, Claude Veillete, Karl Riabowol

Journal:

Experimental Cell Research

Year:

1995

File:

PDF, 1.22 MB

1995

28

701 POSTER Phase I study of oral LBH589 in advanced solid tumours and non-Hodgkin's lymphoma

H.M. Prince, D. George, A. Patnick, M. Mita, P. Atadja, M. Dugan, D. Butterfoss, K. Culver, H.S. Burris, J. Beck

Journal:

European Journal of Cancer Supplements

Year:

2007

Language:

english

File:

PDF, 58 KB

english, 2007

29

Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia

Cao, Fang, Townsend, Elizabeth C., Karatas, Hacer, Xu, Jing, Li, Li, Lee, Shirley, Liu, Liu, Chen, Yong, Ouillette, Peter, Zhu, Jidong, Hess, Jay L., Atadja, Peter, Lei, Ming, Qin, Zhaohui S., Malek,

Journal:

Year:

2014

Language:

english

File:

PDF, 3.55 MB

english, 2014

30

Inhibitors of Human Histone Deacetylase: Synthesis and Enzyme and Cellular Activity of Straight Chain Hydroxamates

Remiszewski, Stacy W., Sambucetti, Lidia C., Atadja, Peter, Bair, Kenneth W., Cornell, Wendy D., Green, Michael A., Howell, Kobporn Lulu, Jung, Manfred, Kwon, Paul, Trogani, Nancy, Walker, Heather

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 242 KB

english, 2002

31

Increased activity of p53 in senescing fibroblasts.

Atadja, P., Wong, H., Garkavtsev, I., Veillette, C., Riabowol, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.88 MB

english, 1995

32

Soluble CD163 in intracerebral hemorrhage: biomarker for perihematomal edema

Roy-O'Reilly, Meaghan, Zhu, Liang, Atadja, Louise, Torres, Glenda, Aronowski, Jaroslaw, McCullough, Louise, Edwards, Nancy J.

Journal:

Annals of Clinical and Translational Neurology

Year:

2017

Language:

english

File:

PDF, 196 KB

english, 2017

33

Erratum: The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

Villagra, Alejandro, Cheng, Fengdong, Wang, Hong-Wei, Suarez, Ildelfonso, Glozak, Michelle, Maurin, Michelle, Nguyen, Danny, Wright, Kenneth L, Atadja, Peter W, Bhalla, Kapil

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 81 KB

english, 2009

34

In bcr-abl-positive myeloid cells resistant to conventional chemotherapeutic agents, expression of Par-4 increases sensitivity to imatinib (STI571) and histone deacetylase-inhibitors

Angela Brieger, Simone Boehrer, Simone Schaaf, Daniel Nowak, Martin Ruthardt, Soo-Zin Kim, Peter Atadja, Dieter Hoelzer, Paris S Mitrou, Eckhart Weidmann, Kai Uwe Chow

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 427 KB

english, 2004

35

702 POSTER Phase I pharmacokinetic and pharmacodynamic study of once-weekly IV LBH589

S. Sharma, N.J. Vogelzang, J. Beck, A. Patnaik, M. Mita, M. Dugan, A. Hwang, K. Culver, P. Atadja, H.M. Prince

Journal:

European Journal of Cancer Supplements

Year:

2007

Language:

english

File:

PDF, 81 KB

english, 2007

36

Treatment with Panobinostat Induces Glucose-Regulated Protein 78 Acetylation and Endoplasmic Reticulum Stress in Breast Cancer Cells

Rao, R., Nalluri, S., Kolhe, R., Yang, Y., Fiskus, W., Chen, J., Ha, K., Buckley, K. M., Balusu, R., Coothankandaswamy, V., Joshi, A., Atadja, P., Bhalla, K. N.

Journal:

Molecular Cancer Therapeutics

Year:

2010

Language:

english

File:

PDF, 941 KB

english, 2010

37

Superior Efficacy of a Combined Epigenetic Therapy against Human Mantle Cell Lymphoma Cells

Fiskus, W., Rao, R., Balusu, R., Ganguly, S., Tao, J., Sotomayor, E., Mudunuru, U., Smith, J. E., Hembruff, S. L., Atadja, P., Marquez, V. E., Bhalla, K.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 979 KB

english, 2012

38

Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation

Zhou, Qun, Atadja, Peter, Davidson, Nancy E.

Journal:

Cancer Biology & Therapy

Year:

2007

Language:

english

File:

PDF, 891 KB

english, 2007

39

Histone deacetylase inhibitor NVP-LAQ824 has significant activity against myeloid leukemia cells in vitro and in vivo

Weisberg, E, Catley, L, Kujawa, J, Atadja, P, Remiszewski, S, Fuerst, P, Cavazza, C, Anderson, K, Griffin, J D

Journal:

Year:

2004

Language:

english

File:

PDF, 278 KB

english, 2004

40

Potentiation of the lethality of the histone deacetylase inhibitor LAQ824 by the cyclin-dependent kinase inhibitor roscovitine in human leukemia cells

Rosato, R. R., Almenara, J. A., Maggio, S. C., Atadja, P., Craig, R., Vrana, J., Dent, P., Grant, S.

Journal:

Molecular Cancer Therapeutics

Year:

2005

Language:

english

File:

PDF, 673 KB

english, 2005

41

Combination of Pan-Histone Deacetylase Inhibitor and Autophagy Inhibitor Exerts Superior Efficacy against Triple-Negative Human Breast Cancer Cells

Rao, R., Balusu, R., Fiskus, W., Mudunuru, U., Venkannagari, S., Chauhan, L., Smith, J. E., Hembruff, S. L., Ha, K., Atadja, P., Bhalla, K. N.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1004 KB

english, 2012

42

Loss of Serum Response Factor Activity Is the Basis of Reduced C-FOS Expression in Aging Human Fibroblasts

Atadja, Peter W., Riabowol, Karl T.

Journal:

Canadian Journal on Aging

Year:

1996

Language:

english

File:

PDF, 2.95 MB

english, 1996

43

FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion

Fan, Yichao, Yue, Jiao, Xiao, Mengtao, Han-Zhang, Han, Wang, Yao Vickie, Ma, Chun, Deng, Zhilin, Li, Yingxiang, Yu, Yanyan, Wang, Xinghao, Niu, Shen, Hua, Youjia, Weng, Zhiping, Atadja, Peter, Li, En,

Journal:

Year:

2017

Language:

english

File:

PDF, 5.44 MB

english, 2017

44

Antitumor activities and on-target toxicities mediated by a TRAIL receptor agonist following cotreatment with panobinostat

Ben P. Martin, Ailsa J. Frew, Michael Bots, Stephen Fox, Fenella Long, Kazuyoshi Takeda, Hideo Yagita, Peter Atadja, Mark J. Smyth, Ricky W. Johnstone

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 716 KB

english, 2011

45

Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors

Lewis Whitehead, Markus R. Dobler, Branko Radetich, Yanyi Zhu, Peter W. Atadja, Tavina Claiborne, Jonathan E. Grob, Andrew McRiner, Margaret R. Pancost, Anup Patnaik, Wenlin Shao, Michael Shultz, Rite

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

46

Detecting S-adenosyl-l-methionine-induced conformational change of a histone methyltransferase using a homogeneous time-resolved fluorescence-based binding assay

Ying Lin, Hong Fan, Mathias Frederiksen, Kehao Zhao, Lei Jiang, Zhaofu Wang, Shaolian Zhou, Weihui Guo, Jun Gao, Shu Li, Edmund Harrington, Peter Meier, Clemens Scheufler, Yao-Chang Xu, Peter Atadja,

Journal:

Analytical Biochemistry

Year:

2012

Language:

english

File:

PDF, 916 KB

english, 2012

47

Correction to: Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia

Salmon, Jessica M., Bots, Michael, Vidacs, Eva, Stanley, Kym L., Atadja, Peter, Zuber, Johannes, Johnstone, Ricky W.

Journal:

Clinical Epigenetics

Year:

2020

File:

PDF, 4.14 MB

2020

48

Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T-cell lymphoma models: Defining molecular mechanisms of resistance

Wenlin Shao, Joseph D. Growney, Yun Feng, Gregory O'Connor, Minying Pu, Wenjing Zhu, Yung-Mae Yao, Paul Kwon, Stephen Fawell, Peter Atadja

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 567 KB

english, 2010

49

A Histone Deacetylase Inhibitor LBH589 Downregulates XIAP in Mesothelioma Cell Lines Which is Likely Responsible for Increased Apoptosis With TRAIL

Symanowski, James, Vogelzang, Nicholas, Zawel, Leigh, Atadja, Peter, Pass, Harvey, Sharma, Sunil

Journal:

Journal of Thoracic Oncology

Year:

2009

Language:

english

File:

PDF, 1.35 MB

english, 2009

50

ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth

Thakur, Satbir, Feng, Xiaolan, Qiao Shi, Zhong, Ganapathy, Amudha, Kumar Mishra, Manoj, Atadja, Peter, Morris, Don, Riabowol, Karl, Katz, Elad

Journal:

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

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